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  1. The cost-effectiveness of magnetic resonance imaging for patients with equivocal neurological symptoms.

    Article - En anglais


    To determine the incremental cost-effectiveness of magnetic resonance imaging (MRI) and computed tomography (CT) in young adults presenting with equivocal neurological signs and symptoms.

    Designs and methods 

    A decision analysis of long-term survival using accuracy data from a diagnostic technology assessment of MRI and CT in patients with suspected multiple sclerosis, information from the medical literature, and clinical assumptions.

    Main results 

    In the baseline analysis, at 30% likelihood of an underlying neurologic disease, MRI use has an incremental cost of $101,670 for each additional quality-adjusted life-year saved compared with $20,290for CT use.

    As the probability of disease increases, further MRI use becomes a cost-effective alternative costing $30,000 for each quality-adjusted life-year saved.

    If a negative MRI result provides reassurance, the incremental costs of immediate MRI use decreases and falls below $25,000 for each quality-adjusted life-year saved no matter the likelihood of disease.


    For most individuals with neurological symptoms or signs, CT imaging is cost-effective while MR imaging is not.

    The cost-effectiveness of MRI use, however, improves as the likelihood of an underlying neurological disease increases.

    For selected patients who highly value diagnostic information, MRI is a reasonable and cost-effective use of medical resources when even the likelihood of disease is quite low (5%).

    Mots-clés Pascal : Imagerie RMN, Tomodensitométrie, Analyse coût efficacité, Economie santé, Système nerveux pathologie, Adulte jeune, Homme, Technique, Evaluation, Diagnostic, Analyse décision, Imagerie médicale, Radiodiagnostic

    Mots-clés Pascal anglais : Nuclear magnetic resonance imaging, Computerized axial tomography, Cost efficiency analysis, Health economy, Nervous system diseases, Young adult, Human, Technique, Evaluation, Diagnosis, Decision analysis, Medical imagery, Radiodiagnosis

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0287008

    Code Inist : 002B30A01C. Création : 15/07/1997.