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  1. International incidence rates of invasive cervical cancer before cytological screening.

    Article - En anglais

    Huge differences in incidence rates of invasive cervical cancer occur among populations.

    These differences reflect the influences of both etiological environmental factors and removal of precursor lesions detected upon screening.

    The purposes of this article are (i) to describe similarities and differences in the shapes and magnitudes of age-specific incidence rates of invasive cervical cancer before screening had an effect, (ii) to provide baseline data for further global study of screening effects, and (iii) to provide baseline incidence data for the design of optimal screening programs.

    To eliminate the impact of screening effects, we have selected age-specific incidence rates from times when and from populations in which screening was insignificant.

    The selected rates were suitably scaled and compared regarding age at onset of increase in incidence, age at peak incidence, and rate of subsequent decline.

    Despite a 16-fold difference in incidence rates, all curves had the same basic structure, with an increase to a peak followed by a decline or a plateau.

    Although all populations but one had an onset around age 25,7 European countries showed an earlier peak age (mean=46 vs. 59) and a more rapid decline after the peak than most other populations.

    The common basic shape of the age-specific incidence curve, overall, suggests a relatively similar development of invasive cervical cancer in different populations. (...)

    Mots-clés Pascal : Tumeur maligne, Col utérus, Age, Incidence, Analyse donnée, Analyse tendance, Echelon international, Méthode statistique, Dépistage, Etude impact, Homme, Femelle, Appareil génital femelle pathologie, Col utérus pathologie

    Mots-clés Pascal anglais : Malignant tumor, Uterine cervix, Age, Incidence, Data analysis, Trend analysis, International scope, Statistical method, Medical screening, Impact study, Human, Female, Female genital diseases, Uterine cervix diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0282386

    Code Inist : 002B20C02. Création : 15/07/1997.