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  1. Asbestos, asbestosis, pleural plaques and lung cancer.

    Article - En anglais

    Inhalation of asbestos fibers increases the risk of bronchial carcinoma.

    It has been claimed that asbestosis is a necessary prerequisite for the malignancy, but epidemiologic studies usually do not have enough statistical strength to prove that asbestos-exposed patients without asbestosis are without risk.

    Several recent studies do actually indicate that there is a risk for such patients.

    In addition, case-referent studies of patients with lung cancer show an attributable risk for asbestos of 6% to 23%, which is much higher than the actual occurrence of asbestosis among these patients.

    Thus there is an increasing body of evidence that, at low exposure levels, asbestos produces a slight increase in the relative risk of lung cancer even in the absence of asbestosis.

    Consequently, all exposure to asbestos must be minimized.

    Mots-clés Pascal : Amiante, Fibre minérale, Toxicité, Tumeur maligne, Bronchopulmonaire, Carcinogène, Homme, Inhalation, Asbestose, Facteur risque, Exposition professionnelle, Médecine travail, Pathogénie, Plaque pleurale, Epidémiologie, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie, Pneumopathie interstitielle, Rat, Rodentia, Mammalia, Vertebrata, Animal

    Mots-clés Pascal anglais : Asbestos, Mineral fiber, Toxicity, Malignant tumor, Bronchopulmonary, Carcinogen, Human, Inhalation, Asbestosis, Risk factor, Occupational exposure, Occupational medicine, Pathogenesis, Pleural plate, Epidemiology, Respiratory disease, Lung disease, Bronchus disease, Interstitial pneumonitis, Rat, Rodentia, Mammalia, Vertebrata, Animal

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0281927

    Code Inist : 002B11A. Création : 15/07/1997.