GB virus-C (GBV-C) and Hepatitis G virus (HGV) are variants of a recently cloned virus transmitted parenterally.
It is unclear if sexual contact also transmits this virus.
In this study, we detected serum GBV-C/HGV RNA in 140 prostitutes by reverse transcription polymerase chain reaction (RT-PCR) using different primers.
Thirty (21%) were found with GBV-C RNA by nested PCR although only 22 (73%) had HGV RNA by single round RT-PCR.
Both assays had a nearly perfect agreement (kappa value, 0.812).
The prevalence of GBV-C RNA in prostitutes was significantly higher than the control group (30/140 vs. 2/40, P<0.02).
Multivariate analysis revealed that a frequency of paid sex more than 120 times per month was the only factor significantly associated with positive GBV-C RNA in prostitutes (P 0.003).
In summary, prostitutes are a high risk group and reservoir of GBV-C/HGV infection due to high frequency of paid-sex.
Mots-clés Pascal : Homme, Femelle, Prostitution, Epidémiologie, Prévalence, Facteur risque, Virose, Infection, Intestin pathologie, Appareil digestif pathologie, Maladie sexuellement transmissible, Virus hépatite GB type C, Virus hépatite G, Hépatite virale GB type C, Hépatite virale G
Mots-clés Pascal anglais : Human, Female, Prostitution, Epidemiology, Prevalence, Risk factor, Viral disease, Infection, Intestinal disease, Digestive diseases, Sexually transmitted disease, Hepatitis GB virus type C, Hepatitis G virus, Viral hepatitis GB type C, Viral hepatitis G
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0281865
Code Inist : 002A05C06. Création : 15/07/1997.