Women and their infants may benefit from therapeutic interventions when hepatitis B, human immunodeficiency virus (HIV), or syphilis are detected during the prenatal period.
We initiated hepatitis B and HIV screening of women attending prenatal clinics in Belize.
Risk factor assessment information for hepatitis B infection and demographic data were determined by interview.
Of 543 evaluable women, 81 (14.9%) were seropositive for hepatitis B core antibody (anti-HBc) ; one woman had asymptomatic hepatitis B surface antigenemia.
Antibodies to HIV-I were detected in one woman.
Reactive syphilis serologies were detected in 15 (2.8%) women.
Anti-HBc seroprevalence varied by district (range 3.1-43.5%) and by ethnicity (range 0.0-40.9%). Significant identified risks for anti-HBc seropositivity from univariate analyses included being of the Garifuna ethnic group, residence or birth in the Stann Creek or Toledo districts, a reactive syphilis serology, a household size of eight or greater, and five or more lifetime sexual partners.
Multivariate analyses identified ethnicity and a reactive rapid plasma reagin as the best predictors of anti-HBc seropositivity.
Highly variable differences in anti-HBc prevalence by district may permit the targeting of limited public health resources for education, screening, and prevention programs.
Mots-clés Pascal : Gestation, Dépistage, Prénatal, Virus hépatite B, Hepadnaviridae, Virus, Virus HIV1, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Femelle, Syphilis, Tréponématose, Spirochétose, Bactériose, Infection, Séropositivité, Belize, Amérique Centrale, Amérique, Homme, Epidémiologie, Maladie sexuellement transmissible
Mots-clés Pascal anglais : Pregnancy, Medical screening, Prenatal, Hepatitis B virus, Hepadnaviridae, Virus, HIV-1 virus, Human immunodeficiency virus, Lentivirinae, Retroviridae, Female, Syphilis, Treponematosis, Spirachaetosis, Bacteriosis, Infection, Seropositivity, Belize, Central America, America, Human, Epidemiology, Sexually transmitted disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0281659
Code Inist : 002B20F01. Création : 15/07/1997.