Extrapulmonary small cell carcinoma (EPSCCA) is often an under-recognized clinicopathologic entity, distinct from small cell lung carcinoma.
The purpose of this study was to review the study institution's experience with EPSCCA with specific emphasis on the epidemiology and response to treatment of these uncommon neoplasms.
Using the tumor registry database of the study institution, the authors retrieved and reviewed the records of all patients with EPSCCA treated between 1974 and 1994.
Study eligibility required that the patients had a normal chest radiograph, computed tomography scan of the chest, sputum cytology, and/or negative bronchoscopy.
Patients with well differentiated neuroendocrine carcinomas and Merkel cell carcinomas of the skin were excluded.
Primary sites of EPSCCA in the current series were : gastrointestinal system in 29 patients, ear, nose, and throat in 14, genitourinary system in 12, internal genitalia in 10, upper respiratory system in 5, unknown primary-lymph nodes in 5, unknown primary-other in 2, the thymus in 3, and the peritoneum in 1. After the initial evaluation and confirmation of histologic diagnosis, 10 of 81 patients had been lost to follow-up.
Of the remaining 71 patients, 54 had limited disease. (...)
Mots-clés Pascal : Carcinome petite cellule, Extrapulmonaire, Homme, Epidémiologie, Site, Pronostic, Traitement, Tumeur maligne
Mots-clés Pascal anglais : Small cell carcinoma, Extrapulmonary, Human, Epidemiology, Site, Prognosis, Treatment, Malignant tumor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0276263
Code Inist : 002B04C. Création : 15/07/1997.