A 40-year analysis of 265 gastric carcinoids.
Gastric carcinoid tumors were previously regarded as rare, benign neoplasms.
Few data are available on the epidemiology of this lesion.
We have analyzed the End Results Group (1950-1969), the Third National Cancer Survey (1969-1971) and the Surveillance, Epidemiology, and End Results (SEER, 1973-1991) databases of the National Cancer Institute.
The three files consist of 8305 carcinoid cases collectively, including 265 gastric carcinoids.
The percentage of gastric carcinoids among all gastric malignancies has increased from 0.3% to 0.54%. The black : white ratio declined from 0.36 to 0.17 as well as the male : female ratio from 0.9 to 0.57.
The age-adjusted incidence rates have increased in white females but are much higher for the black population.
Gastric carcinoids are associated with other malignant neoplasms in 7.8% of cases.
The 5-yr survival rates for localized lesions, with regional and with distant metastases, were 48.6%, 39.9%, and 10%, respectively.
Gastric carcinoids have increased in incidence over the last 20 yr.
This may represent either improved diagnostic techniques, increased awareness, or a real change in incidence.
Poor 5-yr survival rates indicate that gastric carcinoid tumors exhibit an aggressive biological behavior.
Mots-clés Pascal : Tumeur carcinoïde maligne, Estomac, Incidence, Prévalence, Association morbide, Evolution, Pronostic, Etude statistique, Homme, Tumeur maligne, Appareil digestif pathologie, Estomac pathologie
Mots-clés Pascal anglais : Malignant carcinoid tumor, Stomach, Incidence, Prevalence, Concomitant disease, Evolution, Prognosis, Statistical study, Human, Malignant tumor, Digestive diseases, Gastric disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0275824
Code Inist : 002B13B01. Création : 15/07/1997.