Patients with manic episodes represent a substantial subgroup among elderly with mood disorders.
Although the incidence of mania declines across the life span, it may increase again in certain subgroups of the elderly.
For example, late age at onset is often associated with medical and neurologic illness and drug treatments.
Age effects on phenomenology and course have received only preliminary investigation.
Manic episodes in late life may be heterogeneous in terms of representing simply the recurrence of young adult-onset bipolar disorder in late life, the new onset of a bipolar disorder, or a late-onset manic episode in a patient with a history of major depression.
Although aging, diseases, and drug treatments can alter pharmacokinetics and pharmacologic reactions, lithium and more recently the anticonvulsant valproate acid can be useful in acute, continuation, and maintenance treatment of geriatric mania.
Mots-clés Pascal : Trouble bipolaire, Symptomatologie, Traitement, Prévalence, Incidence, Etats Unis, Amérique du Nord, Amérique, Article synthèse, Vieillard, Homme, Trouble humeur, Epidémiologie
Mots-clés Pascal anglais : Bipolar disorder, Symptomatology, Treatment, Prevalence, Incidence, United States, North America, America, Review, Elderly, Human, Mood disorder, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0271457
Code Inist : 002B18E. Création : 15/07/1997.