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  1. Association between migraine and stroke in a large-scale epidemiological Study of the United States.

    Article - En anglais


    To examine the association between stroke and migraine in an epidemiological study.

    Data Sources and Design 

    The National Health and Nutrition Examination Survey baseline and first follow-up data were used to investigate cross-sectional and longitudinal associations between headache/migraine and stroke.


    Study participants from a national probability sample of the civilian noninstitutionalized population of the United States.

    Main Outcome Measure 

    Self-reported physician diagnosis of stroke.


    After controlling for established risk factors for stroke (hypertension, diabetes, heart disease, and gender), both migraine and severe nonspecific headache were associated with a significantly increased risk for stroke reported at follow-up.

    The risk for stroke associated with migraine decreased as the age at stroke increased.


    Our results strengthen previous evidence regarding a nonrandom association of both headache and migraine with stroke, particularly among young women.

    To our knowledge, this is the first systematic examination in a large-scale prospective epidemiological study of men and women with sufficient statistical power to test the association between migraine and stroke in women.

    Severe headache and migraine should be considered as risk factors for the development of stroke, particularly in the absence of other well-established stroke risk factors. (...)

    Mots-clés Pascal : Migraine, Céphalée, Accident cérébrovasculaire, Etats Unis, Amérique du Nord, Amérique, Prospective, Facteur risque, Etude transversale, Etude cohorte, Homme, Douleur, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Cérébrovasculaire pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Trouble neurologique, Epidémiologie

    Mots-clés Pascal anglais : Migraine, Headache, Stroke, United States, North America, America, Prospective, Risk factor, Cross sectional study, Cohort study, Human, Pain, Nervous system diseases, Central nervous system disease, Cerebral disorder, Cerebrovascular disease, Cardiovascular disease, Vascular disease, Neurological disorder, Epidemiology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0268294

    Code Inist : 002B17C. Création : 15/07/1997.