Neuroleptic compliance in a cohort of first episode schizophrenics : A naturalistic study.
Compliance with neuroleptic treatment is difficult for schizophrenic patients, mostly because of objective and subjective side-effects.
Most patients tend to withdraw from medication.
Moreover clinicians are often reluctant to give sufficient doses of neuroleptic after a first episode, though it is recommended.
Our aim was to evidence the clinical practice in a cohort of 59 first episode schizophrenics and the link between compliance, relapse and rehospitalization.
Our results show that during the first year post-discharge, more than 50% of the patients withdraw from neuroleptic.
However, this noncompliant behaviour is not linked to more relapses or more rehospitalizations as could have been expected.
Compliance may have been overscored, since its evaluation depended on variables not as controlled as a blood monitoring.
This study emphasizes the need to improve both patients'compliance and psychiatrists knowledge of neuroleptic therapy in order to achieve better outcome in the course of schizophrenla.
Mots-clés Pascal : Schizophrénie, Psychose, Observance thérapeutique, Neuroleptique, Récidive, Abandon traitement, Hospitalisation, Homme, Chimiothérapie, Traitement, Psychotrope
Mots-clés Pascal anglais : Schizophrenia, Psychosis, Treatment compliance, Neuroleptic, Relapse, Treatment dropout, Hospitalization, Human, Chemotherapy, Treatment, Psychotropic
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0267779
Code Inist : 002B02B03. Création : 15/07/1997.