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  1. Parasitic infections in sickle cell crisis : Nigerian experience.

    Article - En anglais

    Data collected on 150 sickle cell patients in Nigeria were analyzed to determine the frequency of parasitic infections in clinical and hematologic crisis.

    Fifty-three adult and 97 pediatric patients (mean age : 27.6 years and 9.7 years, respectively) were studied.

    Of these patients, 82 were males and 68 were females.

    One hundred thirty-nine had the SS and 11 the SC genotype.

    Blood samples collected from patients on admission for sickle cell-related illnesses were examined microscopically for evidence of Plasmodium sp, and stool samples were analyzed for presence of any helminth.

    A total of 102 parasitic infections associated with clinical cases of sickle cell crisis were recorded (malaria, 36 [35.3% ] ; helminths, 49 [48% ] ; and malaria and helminths together, 17 [16.7% ]). Of the 49 helminthic infections, 26 (53.1%) were due to Ascaris lumbricoides, 15 (30.6%) were due to hookworms, 7 (14.3%) were due to Trichuris trichiura, and 1 (2%) was due to Strongyloides stercoralis.

    The mean hemoglobin levels during clinical crisis were 7.1 g/dL for helminths, 6.4 g/dL for malaria, and 6.1 g/dL for malaria and helminths together.

    Reticulocyte counts were 1.4% for helminths, 1.5% for malaria, and 1.2% for both malaria and helminths together.

    Severity and duration of the clinical crisis were longer for events associated with a single parasitic organism infection than for those with multiple organisms. (...)

    Mots-clés Pascal : Exploration parasitologique, Diagnostic, Association, Anémie, Cellule fusiforme, Dépistage, Pays en développement, Nigéria, Afrique, Examen laboratoire, Evaluation, Homme, Parasitose, Infection, Organisation santé, Hémopathie

    Mots-clés Pascal anglais : Parasitological investigation, Diagnosis, Association, Anemia, Fusiform cell, Medical screening, Developing countries, Nigeria, Africa, Laboratory investigations, Evaluation, Human, Parasitosis, Infection, Public health organization, Hemopathy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0265156

    Code Inist : 002B05E05. Création : 11/06/1997.