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  1. Incidence of and risk factors for hepatitis A in Italy : public health indications from a 10-year surveillance.

    Article - En anglais

    Background/Aims 

    This study aimed to evaluate the incidence of and risk factors for acute viral hepatitis A (HAV) in Italy.

    Methods 

    Data were from a surveillance system for type-specific acute viral hepatitis (SEIEVA).

    To estimate the association of hepatitis A cases with the potential risk factors (Odds Ratios) and the proportion of all hepatitis A cases attributable to a given risk factor (population attributable risk), hepatitis B cases were used as controls.

    Independent predictors of HAV were estimated by conditional multiple logistic regression.

    Results 

    During the period 1985-1994,25553 viral hepatitis cases were reported.

    Of these, 6408 (25%) were due to hepatitis A (HAV).

    HAV incidence declined from 10/100000 in 1985 to 2/100000 in 1987.

    Since 1991, however, an increase in HAV has been observed.

    The majority of cases were 15-24 years old ; the incidence was higher in males and in subjects residing in southern Italy.

    Only one death (0.02%) was observed.

    Shellfish consumption was the most frequently reported risk factor (62%). The proportion of cases reporting personal contact with an icteric case, travel to a high-medium endemic areas, and family contact with a child attending a day-care centre (household of day-care child) was 17%, 19% and 15%, respectively.

    The results of multivariate analysis showed that shellfish consumption (OR=2.6 ; 95% CI=2.4-2.9), travel to endemic areas for people residing in northern and central Italy (OR=5.4 ; 95% CI=4.6-6. (...)

    Mots-clés Pascal : Hépatite virale A, Virose, Infection, Aigu, Virus hépatite A, Picornaviridae, Virus, Incidence, Facteur risque, Contamination, Alimentation, Epidémiologie, Homme, Italie, Europe, Appareil digestif pathologie, Foie pathologie

    Mots-clés Pascal anglais : Viral hepatitis A, Viral disease, Infection, Acute, Hepatitis A virus, Picornaviridae, Virus, Incidence, Risk factor, Contamination, Feeding, Epidemiology, Human, Italy, Europe, Digestive diseases, Hepatic disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0264117

    Code Inist : 002B30A01A2. Création : 11/06/1997.