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  1. The EPIC project : Rationale and study design.

    Article - En anglais

    Background

    The most consistent result of epidemiological studies on diet and cancer is that a diet rich in vegetables, fruit and, more generally, in plant foods is associated with a reduced risk of cancer at several anatomical sites.

    Epidemiological studies have been less consistent regarding the putative increase in risk related to consumption of fat or meat.

    In addition it has not been possible to identify clearly the biological role of specific nutrients or non-nutrient food components in the prevention or causation of cancer.

    Limitations in the precision and validity of traditional dietary intake measurements and limited use of biomarkers combined with narrow ranges of variations in dietary habits within single populations, have been the main reasons for the limited success in identifying more specific diet and cancer links.

    Methods

    EPIC is a multi-centre prospective cohort study designed to investigate the relation between diet, nutritional and metabolic characteristics, various lifestyle factors and the risk of cancer.

    The study is based in 22 collaborating centres in nine European countries and includes populations characterized by large variations in dietary habits and cancer risk.

    Data are collected on diet, physical activity, sexual maturation and reproductive history, lifetime consumption of alcohol and tobacco, previous and current illnesses and current medication. (...)

    Mots-clés Pascal : Tumeur maligne, Epidémiologie, Etude multicentrique, Prospective, Europe, Régime alimentaire, Nutrition, Marqueur biologique, Homme, Projet EPIC

    Mots-clés Pascal anglais : Malignant tumor, Epidemiology, Multicenter study, Prospective, Europe, Diet, Nutrition, Biological marker, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0261305

    Code Inist : 002B30A01A2. Création : 11/06/1997.