The purpose of this study was to evaluate the benefits of intraoperative autotransfusion of autologous blood on the conservation of allogenic blood, including cost-effectiveness and the consequences for hemoglobin level and coagulation tests.
The Haemonetics Cell Saver 4 autotransfusion system (Haemonetics Corporation, MA) was used when the estimated blood loss was equal to or more than 500 ml.
A total of 472 patients undergoing intracranial surgery were included in the study.
Ninety patients (19%) received transfusions either with autologous blood or allogenic blood.
Fifty-five patients (61%) received only autologous blood transfusions, 10 patients (11%) received both autologous and allogenic blood transfusions, and 25 patients (28%) received only allogenic blood transfusions.
The amount of autologous blood transfused was 600 ± 590 ml (range, 230-3000 ml).
The amount of allogenic blood transfused was 3 ± 3 units (range, 2-15 units).
Autologous blood represented 68% of all blood products transfused.
Mild abnormalities during coagulation tests occurred without clinical bleeding.
Autologous blood transfusions were demonstrated to be safe in patients undergoing intracranial surgery and to be more cost-effective than allogenic blood transfusions. (...)
Mots-clés Pascal : Chirurgie, Intracrânien, Transfusion, Sang, Système autologue, Peropératoire, Analyse avantage coût, France, Europe, Homme, Economie santé
Mots-clés Pascal anglais : Surgery, Intracranial, Transfusion, Blood, Autologous system, Intraoperative, Cost benefit analysis, France, Europe, Human, Health economy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0259891
Code Inist : 002B25J01. Création : 11/06/1997.