Using data from the surveillance system for acute viral hepatitis we have evaluated the case fatality rate of viral hepatitis in Italy. 71 deaths (0.3%) occurred among the 21,553 reported acute viral hepatitis cases from 1985-1994.
None reported history of exposure to drugs or toxins.
The highest case fatality rate was observed for B and NANB hepatitis (0.5%). One death occurred among the 6,353 (0.02%) hepatitis A cases and 1 among the 909 (0.1%) anti-HCV positive NANB hepatitis cases.
The case fatality for Delta hepatitis was 0.2% (1/422).
Case fatality rate was similar in both sexes ; increasing with age ; 0.03% were<15 years of age, 0.1%, 15-24 year-old, and 0.5% =25 years.
Subjects older than 24 years of age accounted for 81.4% of total deaths.
Intravenous drug use, blood transfusion and other parenteral exposures were the three most frequent non-mutally exclusive sources of infection reported by subjects who died from B and NANB hepatitis.
These findings indicate that the survival rate of acute B and NANB hepatitis is lower than that of acute hepatitis A ; moreover in Italy, as in other Western countries, acute HCV seems to cause liver failure only rarely.
Mots-clés Pascal : Hépatite virale, Virose, Infection, Aigu, Epidémiologie, Etiologie, Homme, Mortalité, Italie, Europe, Surveillance sanitaire, Pronostic, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Viral hepatitis, Viral disease, Infection, Acute, Epidemiology, Etiology, Human, Mortality, Italy, Europe, Sanitary surveillance, Prognosis, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0259585
Code Inist : 002B05C02G. Création : 11/06/1997.