A thyroid-hormone evaluation of workers dealing with cyanide compounds in an electroplating process of a cable industry was carried out.
Serum thiocyanate (SCN) levels of 35 nonsmoking copper-ply employees were assayed by a ferric-chloride color test.
The mean SCN concentration of these employees was 316 ± 15 mumol/L, which was significantly (P<0.01) higher than that of control subjects (90.8 ± 9.02 mumol/L).
Serum thyroxine (T4), triiodothyronine (T3), and thyroid-stimulating hormone (TSH) concentrations of exposed workers were compared with those of 35 control subjects.
Cyanide exposure resulted in a decrease in T4 and T3 concentrations (P<0.05) and an increase in TSH concentration (P<0.05), compared with the control subjects.
The serum T4 level was found to be negatively correlated (r=-0.363, P<0.05), whereas the TSH level was positively correlated (r=0.354, P<0. 05), with SCN concentration in the exposed group.
The study suggests that occupational cyanide exposure in the industry impairs thyroid function.
Mots-clés Pascal : Cyanure, Exposition professionnelle, Médecine travail, Toxicité, Homme, Dépôt électrolytique, Surveillance biologique, Thyroïde, Hormone thyroïdienne, Epidémiologie, Inde, Asie, Endocrinopathie
Mots-clés Pascal anglais : Cyanides, Occupational exposure, Occupational medicine, Toxicity, Human, Electrodeposition, Biological monitoring, Thyroid gland, Thyroid hormone, Epidemiology, India, Asia, Endocrinopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0255449
Code Inist : 002B03L05. Création : 11/06/1997.