Clinical trials have demonstrated that use of mammographic screening and advances in therapy can improve prognosis for women with breast cancer.
We determined the trends in breast cancer mortality rates, as well as incidence and survival rates by extent of disease at diagnosis, for white women in the United States and considered whether these trends are consistent with widespread use of such beneficial medical interventions.
We examined mortality data from the National Center for Health Statistics and incidence and survival data by extent of disease from the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute, all stratified by patient age, using statistical-regression techniques to determine changes in the slope of trends over time.
The age-adjusted breast cancer mortality rate for U.S. white females dropped 6.8% from 1989 through 1993.
A significant decrease in the slope of the mortality trend of approximately 2% per year was observed in every decade of age from 40 to 79 years of age.
Trends in incidence rates were also similar among these age groups :
localized disease rates increased rapidly from 1982 through 1987 and stabilized or increased more slowly thereafter ;
regional disease rates decreased after 1987 ;
and distant disease rates have remained level over the past 20 years. (...)
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Incidence, Survie, Mortalité, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Homme, Glande mammaire pathologie
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Incidence, Survival, Mortality, Epidemiology, United States, North America, America, Human, Mammary gland diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0253691
Code Inist : 002B20E02. Création : 11/06/1997.