Objectives-After an inquiry from the employees of an offset printing plant, a historical cohort study was conducted to investigate cancer mortality among these workers.
Methods-The cohort comprised 262 men, who contributed 2771 person-years of observation. 16 deaths were identified during the follow up period (1980-91).
Expected numbers of deaths were derived from age specific regional rates.
Standardised mortality ratios (SMR) and 95% confidence intervals (95% CIs) were calculated.
An increased cancer mortality was found after 10 years of employment (SMR 213,95% CI 98 to 405, based on nine deaths), mainly due to a high mortality from lung cancer (SMR 381,95% CI 104 to 975, four deaths), and from oesophageal cancer (SMR 1049,95% CI 216 to 3065, three deaths).
For workers with at least 20 years since the start of employment, the SMR was 262 (95% CI 105 to 540) for all cancer sites, 447 (95% CI 92 to 1306) for lung cancer, and 1094 (95% CI 132 to 3952) for oesophageal cancer.
The increased cancer mortality was concentrated among pressmen.
Conclusion-Although based on small numbers, the findings suggest an increased risk of cancer among these workers, which should be further investigated.
Mots-clés Pascal : Imprimerie, Exposition professionnelle, Médecine travail, Tumeur maligne, Bronchopulmonaire, Oesophage, Homme, Mortalité, Epidémiologie, Etude cohorte, Rapport standardisé mortalité, France, Europe, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie, Appareil digestif pathologie, Oesophage pathologie
Mots-clés Pascal anglais : Printing plant, Occupational exposure, Occupational medicine, Malignant tumor, Bronchopulmonary, Esophagus, Human, Mortality, Epidemiology, Cohort study, Standardized mortality ratio, France, Europe, Respiratory disease, Lung disease, Bronchus disease, Digestive diseases, Esophageal disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0246827
Code Inist : 002B04B. Création : 11/06/1997.