Increased interest in the potential cardio-protective effects of fruit and vegetables is currently unsupported by systematic reviews of the reported associations of these foods with risk.
All ecological, case-control, cohort studies and unconfounded trials in humans were eligible for inclusion.
Eligible outcomes were symptomatic coronary heart disease, stroke and total circulatory disease.
Only studies of diet that reported on fresh fruit and vegetables or a nutrient which could serve as a proxy (reversing the usual direction of inference) were included.
MEDLINE (1966-1995) and EMBASE (1980-1995) were searched using the terms cerebrovascular disorder, coronary heart disease, fruit (s) and vegetable (s) as keywords.
Personal bibliographies, books and reviews were also searched, as were citations in located reports.
For coronary heart disease nine of ten ecological studies, two of three case-control studies and six of 16 cohort studies found a significant protective association with consumption of fruit and vegetables or surrogate nutrients.
For stroke three of five ecological studies, none (of one) case-control study and six of eight cohort studies found a significant protective association with consumption of fruit and vegetables or surrogate nutrients.
For total circulatory disease, one of two cohort studies reported a significant protective association. (...)
Mots-clés Pascal : Régime alimentaire, Fruit, Légume, Appareil circulatoire pathologie, Epidémiologie, Incidence, Facteur risque, Homme, Prévention, Revue bibliographique, Alimentation
Mots-clés Pascal anglais : Diet, Fruit, Vegetable, Cardiovascular disease, Epidemiology, Incidence, Risk factor, Human, Prevention, Bibliographic review, Feeding
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0245163
Code Inist : 002B12A03. Création : 11/06/1997.