To determine the prevalence and severity of uveitis in an outpatient pediatric arthritis clinic in the midwestern United States during the 1990s.
The prevalence and clinical characteristics of uveitis were studied retrospectively for all children diagnosed with arthritis at Shriner's Hospital for Crippled Children and followed by the pediatric rheumatology and ophthalmology units of the St Louis Children's Hospital between 1992 and 1995.
Seven children (9%) developed uveitis in a population of 78 patients with juvenile arthritis.
Six of the seven children were female, and all six females had antinuclear antibody (ANA) - positive, juvenile rheumatoid arthritis (JRA).
The prevalence of anterior uveitis in females with ANA-positive, pauciarticular JRA was 20%, and in polyarticular JRA, 17%. One of the girls with uveitis had combined JRA and sarcoidosis ; the boy with uveitis had juvenile spondylitis.
Arthritis preceded the onset of uveitis in each child by 1 to 13 years (average, 6.4 years).
Progression of the uveitis in three of the children resulted in band keratopathy and cataract, causing significant visual loss in two (ie, in 29% of the children who developed uveitis).
The prevalence and ocular morbidity of uveitis in juvenile arthritis'appears to have remained relatively stable over the last 2 decades. (...)
Mots-clés Pascal : Arthrite chronique juvénile, Uvéite, Prévalence, Indice gravité, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Symptomatologie, Enfant, Homme, Chronique, Système ostéoarticulaire pathologie, Rhumatisme inflammatoire, Oeil pathologie, Uvée pathologie
Mots-clés Pascal anglais : Juvenile rheumatoid arthritis, Uveitis, Prevalence, Severity score, United States, North America, America, Epidemiology, Symptomatology, Child, Human, Chronic, Diseases of the osteoarticular system, Inflammatory joint disease, Eye disease, Uvea disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0241996
Code Inist : 002B09F. Création : 11/06/1997.