The risk of breast cancer associated with delivering a twin birth was examined in a population-based nested case - control study of nearly 4800 Swedish women with breast cancer and 47000 age-matched control subjects.
All were aged less than 50 years and parous.
After adjustment for age at first birth and parity, a 29% reduction in breast cancer risk was observed in mothers of twins relative to those who were not (odds ratio=0.71,95% confidence interval 0.55-0.91).
These results provide evidence that women who bear twins are at reduced risk of breast cancer, one explanation for which may be their unusual levels of hormonal exposure.
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Epidémiologie, Gestation gémellaire, Suède, Europe, Homme, Glande mammaire pathologie
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Epidemiology, Twin pregnancy, Sweden, Europe, Human, Mammary gland diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0232819
Code Inist : 002B20E02. Création : 11/06/1997.