Many patients with previous poliomyelitis develop'post-polio syndrome' (PPS) in which late functional deterioration follows a period of relative stability.
The frequency with which PPS can be attributed to clearly defined causes remains uncertain.
We reviewed 283 newly-referred patients with previous poliomyelitis seen consecutively over a 4-year period ; 239 patients developed symptoms of functional deterioration at a mean of 35 (5-65) years after the paralytic illness.
Functional deterioration was associated with orthopaedic disorders in 170 cases, neurological disorders in 35, respiratory disorders in 19 and other disorders in 15.
Progressive post-polio muscular atrophy was not observed.
Functional deterioration following paralytic poliomyelitis is common, and associated with orthopaedic, neurological, respiratory and general medical factors which are potentially treatable.
Mots-clés Pascal : Poliomyélite antérieure, Virose, Infection, Paralysie, Incidence, Complication, Etude cohorte, Forme clinique, Détérioration, Etiologie, Facteur risque, Prévention, Long terme, Homme, Article synthèse, Système nerveux pathologie, Système nerveux central pathologie, Moelle épinière pathologie, Organisation santé
Mots-clés Pascal anglais : Acute anterior poliomyelitis, Viral disease, Infection, Paralysis, Incidence, Complication, Cohort study, Clinical form, Deterioration, Etiology, Risk factor, Prevention, Long term, Human, Review, Nervous system diseases, Central nervous system disease, Spinal cord disease, Public health organization
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0229267
Code Inist : 002B17I. Création : 11/06/1997.