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  1. The prognosis of chronic fatigue and chronic fatigue syndrome : a systematic review.

    Article - En anglais

    The prognosis of chronic fatigue syndrome and chronic fatigue has been studied in numerous small case series.

    We performed a systematic review of all studies to determine the proportion of individuals with the conditions who recovered at follow-up, the risk of developing alternative physical diagnoses, and the risk factors for poor prognosis.

    A literature search of all published studies which included a follow-up of patients with chronic fatigue syndrome or chronic fatigue were performed.

    Of 26 studies identified, four studied fatigue in children, and found that 54-94% of children recovered over the periods of follow-up.

    Another five studies operationally defined chronic fatigue syndrome in adults and found that<10% of subjects return to pre-morbid levels of functioning, and the majority remain significantly impaired.

    The remaining studies used less stringent criteria to define their cohorts.

    Among patients in primary care with fatigue lasting<6 months, at least 40% of patients improved.

    As the definition becomes more stringent the prognosis appears to worsen.

    Consistently reported risk factors for poor prognosis are older age, more chronic illness, having a comorbid psychiatric disorder and holding a belief that the illness is due to physical causes.

    Mots-clés Pascal : Fatigue chronique syndrome, Diagnostic différentiel, Fatigue, Dépistage, Critère sélection, Etiologie, Facteur risque, Synthèse bibliographique, Etude comparative, Facteur prédictif, Evaluation, Homme, Enfant, Système nerveux pathologie

    Mots-clés Pascal anglais : Chronic fatigue syndrome, Differential diagnostic, Fatigue, Medical screening, Selection criterion, Etiology, Risk factor, Bibliographic survey, Comparative study, Predictive factor, Evaluation, Human, Child, Nervous system diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0229123

    Code Inist : 002B18C14. Création : 11/06/1997.