Predicting factors for absenteeism in patients with major depressive disorders.
This study examines the predicting factors for absenteeism in depressed patients.
Using a'cross-sectional'design, we observed 345 patients diagnosed with major depressive disorders as assessed by the Diagnostic and Statistical Manual for Mental Disorders, third edition revised (DSM-III-R) criteria and Hamilton Depression Rating Scale (HAM-D)  score higher than 12.
The treatment group (n=268) were treated with antidepressants (n=98 with fluoxetine and n=170 with tricyclics [amitriptyline, clomipramine]) for at least one week and the non treated group (n=67) had not received antidepressants for at least one month.
Sociodemographic, clinical and therapeutic data was collected.
The primary endpoint was absenteeism from work.
Logistic regression analysis of these data was used to identify potential predictive variables.
The rate of absenteeism from work was greater in non treated (70.2%) compared to treated patients (39.8% for fluoxetine group and 57.7% for tricyclics group).
The risk of absenteeism for patients treated with tricyclics was 2.45 times greater than for patients treated with fluoxetine (odds-ratio=2.45, Cl 95%=1.1-4.7).
For all patients, the strongest predictors of absenteeism from work were symptom severity (odds-ratio=44.4, CI 95%=7.9-250) followed by past history of depression (odds-ratio=6.85, CI 95%=2.6-18.4) and past history of absenteeism (odds-ratio=6.51, CI 95%=2.0-204). (...)
Mots-clés Pascal : Etat dépressif, Indice gravité, Antidépresseur, Absentéisme, Activité professionnelle, Aptitude à l'emploi, Epidémiologie, Prédiction, Indicateur, Echelle évaluation, Homme, Médecine travail, France, Europe, Trouble humeur
Mots-clés Pascal anglais : Depression, Severity score, Antidepressant agent, Absenteeism, Professional activity, Fitness for purpose, Epidemiology, Prediction, Indicator, Evaluation scale, Human, Occupational medicine, France, Europe, Mood disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0227509
Code Inist : 002B18C07A. Création : 11/06/1997.