A case-control study of 100 newly diagnosed patients with Graves'disease and the same numbers of controls matched with respect to sex, age (± 2 years) and type of residence (rural-urban) was carried out.
According to the matched analysis (McNemar's test and t-test) seventeen variables recognized as risk factors were included into the model of multivariate conditional logistic regression.
The following factors were significantly associated with the occurrence of Graves'disease : change in time spent on work - much overtime work, second job, much less work than usual (RR=6.62 ; CI=2.08-21.01), lack of readiness of relatives and friends to help the subject (RR=1.48 ; 95% CI=1.14-1.93), increased arguments with spouse (RR=14.12 ; 95% CI=1.63-121.87), unemployment for at least one month (RR=9.80 ; 95% CI=1.13-85.02), and family history of Graves disease in the first degree of relation (RR=7.20 ; 95% CI=0.85-60.70).
Mots-clés Pascal : Basedow maladie, Epidémiologie, Facteur risque, Homme, Etude cas témoin, Yougoslavie, Europe, Endocrinopathie, Thyroïde pathologie, Hyperthyroïdie, Immunopathologie, Maladie autoimmune
Mots-clés Pascal anglais : Graves disease, Epidemiology, Risk factor, Human, Case control study, Yugoslavia, Europe, Endocrinopathy, Thyroid diseases, Hyperthyroidism, Immunopathology, Autoimmune disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0227504
Code Inist : 002B21C01. Création : 11/06/1997.