In order to evaluate the presence of HTLV-II infection in a cohort of newborns born from HIV-I infected mothers, a retrospective study was conducted on 80 newborns.
Only I birth serum sample (1.25%) was found seropositive for HTLV-II by Western Blot suggesting a transplacental transmission of anti-HTLV-II antibodies.
Two consecutive PCR performed on PBMCs of the seropositive newborn resulted negative suggesting the absence of the infection.
More extensive studies are needed to assess the risk of transmission in areas with a higher prevalence of HTLV-II infection.
Mots-clés Pascal : Virus HTLV2, Retroviridae, Virus, SIDA, Virose, Infection, Virus HIV1, Virus immunodéficience humaine, Lentivirinae, Mère, Sérologie, Prévalence, Risque, Transmission, Nouveau né, Homme, Epidémiologie, Italie, Europe, Etude cohorte, Immunopathologie, Immunodéficit, Gestation pathologie
Mots-clés Pascal anglais : HTLV-II virus, Retroviridae, Virus, AIDS, Viral disease, Infection, HIV-1 virus, Human immunodeficiency virus, Lentivirinae, Mother, Serology, Prevalence, Risk, Transmission, Newborn, Human, Epidemiology, Italy, Europe, Cohort study, Immunopathology, Immune deficiency, Pregnancy disorders
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0226764
Code Inist : 002B06D01. Création : 11/06/1997.