A geographically based sample of 1069 Hispanic and non-Hispanic white persons aged 20-74 years, living in southern Colorado and who tested normal on an oral glucose tolerance test (World Health Organization criteria) were evaluated to determine associations of dietary factors with fasting serum insulin concentrations.
Subjects were seen for up to three visits from 1984 to 1992.
A 24-h diet recall and fasting insulin concentrations were collected at all visits.
In longitudinal data analysis, lower age, female gender, Hispanic ethnicity, higher body mass index, higher waist circumference, and no vigorous activity were significantly related to higher fasting insulin concentrations.
High total and saturated fat intake were associated with higher fasting insulin concentrations after adjusting for age, sex, ethnicity, body mass index, waist circumference, total energy intake and physical activity.
Dietary fibre and starch intake were inversely associated with fasting insulin concentrations.
No associations with fasting insulin concentrations were observed for monounsaturated fat, polyunsaturated fat, sucrose, glucose and fructose intake.
Associations were similar in men and women and for active and inactive subjects, though associations of fibre and starch intake with insulin concentrations were strongest in lean subjects. (...)
Mots-clés Pascal : Résistance tissu cible, Insuline, Macronutriment, Facteur risque, Etiologie, Pronostic, Diabète, Hormone pancréatique, Endocrinopathie, Homme, Epidémiologie, Colorado, Etats Unis, Amérique du Nord, Amérique, Hispanique
Mots-clés Pascal anglais : Target tissue resistance, Insulin, Macronutrient, Risk factor, Etiology, Prognosis, Diabetes mellitus, Pancreatic hormone, Endocrinopathy, Human, Epidemiology, Colorado, United States, North America, America
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0220648
Code Inist : 002B30A01A2. Création : 21/05/1997.