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  1. The prevalence of gastro-oesophageal reflux disease based on non-specific symptoms in institutionalized, intellectually disabled individuals.

    Article - En anglais


    The prevalence of gastro-oesophageal reflux disease (GORD) in randomly selected, institutionalized, intellectually disabled individuals (lQ<50) in The Netherlands is high.


    In this study we investigated the prevalence of GORD and reflux oesophagitis (RO) in intellectually disabled individuals specifically selected for symptoms such as : behavioural difficulties such as automutilation, food refusal, fear and restlessness, vomiting, regurgitation and rumination.

    Predisposing factors were also evaluated.


    One hundred and ten individuals from one institute underwent a 24-h oesophageal pH test and were scored for predisposing factors and non-specific reflux symptoms.

    A pathological pH test was defined as a pH lower than 4 more than 4.5% of the measured time.

    Subjects with a pathological pH test (patients) were compared to those with a normal pH test (controls).


    In seven cases (6.4%) the test failed for technical reasons.

    In 57 (55.3%) cases a pathological pH test was found.

    RO was diagnosed in 33 (64.7%) patients

    The use of anticonvulsant drugs and cerebral palsy appeared to be predisposing factors, while the non-specific reflux symptoms did not discriminate for GORD.


    The prevalence of GORD was equal in a randomly selected group of intellectually disabled individuals, and in this group, specifically selected on account of possible reflux symptoms. (...)

    Mots-clés Pascal : Déficit, Intelligence, Association morbide, Reflux gastrooesophagien, Symptomatologie, Prévalence, Epidémiologie, Homme, Pays Bas, Europe, Psychopathologie, Appareil digestif pathologie, Oesophage pathologie

    Mots-clés Pascal anglais : Deficiency, Intelligence, Concomitant disease, Gastroesophageal reflux, Symptomatology, Prevalence, Epidemiology, Human, Netherlands, Europe, Psychopathology, Digestive diseases, Esophageal disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0219814

    Code Inist : 002B13A03. Création : 21/05/1997.