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  1. Exercise induced bronchospasm in Ghana : differences in prevalence between urban and rural schoolchildren.

    Article - En anglais


    As more developing countries adopt a westernised style of living, an increase in the prevalence of asthma can be expected to occur in these areas.

    A study was undertaken to establish the normal response to exercise in Ghanaian children and to use these normal values to determine the prevalence of exercise induced bronchospasm (EIB) in urban rich (UR), urban poor (UP), and rural (R) school children.

    Skin test reactivity to common inhalant allergens in UR, UP, and R children with and without EIB was also investigated.


    Two hundred children aged 9-16 years without a previous history of respiratory symptoms were randomly selected and underwent free running exercise testing.

    A normal response to exercise was defined as the group mean change in peak expiratory flow rate (PEFR)+2 standard deviations.

    This value was used to identify the prevalence of EIB in UR, UP, and R schoolchildren.

    A total of 1095 children from three different schools underwent exercise testing (220 UP, 599 UR, 276 R), after which 916 children underwent skin prick testing to six common inhalant allergens (D farinae, D pteronyssinus, cat, dog, Aspergillus flavus and Candida albicans).


    From the results of exercise testing in asymptomatic children the normal range was defined as a fall in PEFR of<12.5% after exercise.

    Thirty four children were classified as having EIB on the basis of the above definition, giving an overall prevalence of 3.1%. (...)

    Mots-clés Pascal : Asthme, Allergie, Exercice physique, Prévalence, Milieu urbain, Milieu rural, Ghana, Afrique, Enfant, Homme, Etude comparative, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Immunopathologie, Epidémiologie

    Mots-clés Pascal anglais : Asthma, Allergy, Physical exercise, Prevalence, Urban environment, Rural environment, Ghana, Africa, Child, Human, Comparative study, Respiratory disease, Obstructive pulmonary disease, Immunopathology, Epidemiology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0219525

    Code Inist : 002B06C02. Création : 21/05/1997.