This report describes data collected by the Italian Registry of Renal Biopsies (IRRB) (E mail http :/www. teseo. it/nephrology/irrb), which includes 15 461 renal biopsies (RB) performed over a period of 7 years (1987-1993).
From 1987 to 1988, the Registry recorded only the histological diagnosis of 3686 RB, whereas beginning in 1989, additional records (sex, age, clinical symptoms and renal function) were obtained from 11 775 patients undergoing RB.
This is the first report on such a large number of RB containing data from 96% of Italian renal units which routinely perform RB.
In 13 835 RB performed in native kidneys, two groups of renal diseases, primary (59.9%) and secondary (25.4%) glomerulonephritis (gn), were more frequent than others.
Among primary gn, the frequency of cases of IgAN, membranous gn, and focal and segmental glomerulosclerosis were 36.9,21.7 and 10.4% respectively.
Renal disease due to immune-mediated causes (51%) and dysgammaglobulinaemia (26.9%) were the most frequent among secondary gn.
In the former group, the frequency of cases with lupus nephritis and vasculitis were 51.6 and 25.9% respectively.
Renal amyloidosis (39.3%), essential mixed cryoglobulinaemia (30.9%), and multiple myeloma were the most frequent forms in the latter group.
In 1993 the incidence of the following groups of renal disease was : primary gn (22.7 p.m.p.), secondary gn (11.1 p.m.p.) of which immune-mediated gn (5.8 p.m.p. (...)
Mots-clés Pascal : Rein pathologie, Diagnostic, Biopsie, Exploration cytologique, Maladie, Incidence, Néphropathie glomérulaire, Registre, Epidémiologie, Homme, Appareil urinaire pathologie, Anatomopathologie
Mots-clés Pascal anglais : Kidney disease, Diagnosis, Biopsy, Cytologic investigation, Disease, Incidence, Glomerulonephritis, Register, Epidemiology, Human, Urinary system disease, Pathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0217125
Code Inist : 002B24O07. Création : 21/05/1997.