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  1. The distribution of total and specific serum IgE in the European Community Respiratory Health Survey.

    Article - En anglais

    Background 

    Variations in the prevalence of atopy could provide important clues to the etiology of atopy and asthma.

    Although estimates of prevalence are available from different studies, a lack of standardization makes comparisons difficult.

    Objective 

    This study was conducted to estimate the variation of geometric mean levels of serum IgE and the prevalence of specific IgE to common allergens between populations as part of the European Community Respiratory Health Survey (ECRHS), a multicenter survey of asthma and risk factors for asthma.

    Methods 

    Random samples of subjects living in 37 centers in 16 countries who had answered a questionnaire about their respiratory symptoms were invited for further assessment including total serum IgE and the presence of specific IgE against house dust mite (Dermatophagoides pteronyssinus), timothy grass, cat, Cladosporium herbarum, and a local allergen.

    Sera were tested from 13,883 persons.

    Results 

    The estimated prevalence of atopy, defined as the presence of at least one positive specific IgE, ranged from 16% in Albacete (Spain) to 45% in Christchurch (New Zealand).

    The geometric mean total serum IgE varied from 13 kU/L in Reykjavik (Iceland) to 62 kU/L in Bordeaux (France).

    There was no relation between the geometric mean total serum IgE in a center and the prevalence of atopy.

    Conclusions 

    There are substantial variations in the prevalence of atopy and the level of serum IgE. (...)

    Mots-clés Pascal : Asthme, Pollen, Allergène, Atopie, Prévalence, Sérologie, IgE, Poussière maison, Dermatophagoides pteronyssinus, Pyroglyphidae, Acaridida, Acariformes, Acari, Arachnida, Arthropoda, Invertebrata, Gramineae, Monocotyledones, Angiospermae, Spermatophyta, Cladosporium herbarum, Fungi Imperfecti, Fungi, Thallophyta, Betula, Betulaceae, Dicotyledones, Epidémiologie, Chat, Fissipedia, Carnivora, Mammalia, Vertebrata, Animal, Europe, Arbre, Homme, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Urticaceae, Compositae, Immunopathologie, Allergie, Parietaria judaica, Ambrosia, Pneumallergène

    Mots-clés Pascal anglais : Asthma, Pollen, Allergen, Atopy, Prevalence, Serology, IgE, House dust, Dermatophagoides pteronyssinus, Pyroglyphidae, Acaridida, Acariformes, Acari, Arachnida, Arthropoda, Invertebrata, Gramineae, Monocotyledones, Angiospermae, Spermatophyta, Cladosporium herbarum, Fungi Imperfecti, Fungi, Thallophyta, Betula, Betulaceae, Dicotyledones, Epidemiology, Cat, Fissipedia, Carnivora, Mammalia, Vertebrata, Animal, Europe, Tree, Human, Respiratory disease, Obstructive pulmonary disease, Urticaceae, Compositae, Immunopathology, Allergy, Aeroallergen

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0214567

    Code Inist : 002B06C02. Création : 21/05/1997.