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  1. Genital Chlamydia infections in sexually active female adolescents : Do we really need to screen everyone ?

    Article - En anglais

    Purpose 

    To evaluate current Chlamydia trachomatis screening guidelines, which recommend that all sexually active female adolescents undergoing a pelvic examination be tested for chlamydial infection, and determine if instead providers should target particular subpopulations of these adolescents.

    Methods 

    Data were collected from 148,650 sexually active females, ages 15-19 years, tested by direct immunofluorescent antibody in 160 family planning clinics from 1988-92.

    Trends in chlamydia prevalence by demographic, behavioral, and clinical risk factors were analyzed.

    Logistic regression modeling was used to identify selective screening criteria.

    Predictive models were developed for all years combined, as well as for the years when prevalence was highest and lowest.

    Results 

    The prevalence of C. trachomatis in this population was 10%, with a 42% decrease (13.2-7.6%) over the 5-year period.

    Logistic regression identified nine demographic, behavioral, and clinical predictors (p<0.0001) associated with chlamydial infections.

    Predictor models from the highest and lowest prevalence years varied little from the combined model.

    Individual year predictor models showed poor sensitivity and were similar for these 2 years.

    The screening criteria could not identify a group of adolescents with a prevalence less than 6%. Conclusions : Several individual risk factors were strongly associated with C. (...)

    Mots-clés Pascal : Chlamydia trachomatis, Chlamydiaceae, Chlamydiales, Bactérie, Dépistage, Adolescent, Homme, Chlamydiose, Bactériose, Infection, Appareil génital femelle pathologie, Prise risque, Relation sexuelle, Epidémiologie, Facteur risque, Prévalence, Femelle

    Mots-clés Pascal anglais : Chlamydia trachomatis, Chlamydiaceae, Chlamydiales, Bacteria, Medical screening, Adolescent, Human, Chlamydiosis, Bacteriosis, Infection, Female genital diseases, Risk taking, Sexual intercourse, Epidemiology, Risk factor, Prevalence, Female

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0213391

    Code Inist : 002B05B02H. Création : 21/05/1997.