This study examined the association between occupational chemical and radiation exposures and risk of medically diagnosed infertility in 281 women compared with 216 fertile women.
After adjustment for age and exposures that occurred before case/referent ascertainment, there was an increased risk of infertility among those women exposed to volatile organic solvents (odds ratio [OR], 1.74 ; 95% confidence interval [CI], 1.11 to 2.71), chemical dusts (OR, 2.66 ; CI, 1.17 to 6.05), pesticides (OR, 3.02 ; (CI, 1.10 to 8.29), and video display terminals (OR, 2.21, CI, 1.22 to 4.01).
Among the medically diagnosed causes of infertility the adjusted risk associated with having an ovulatory factor increased among those women exposed to solvents (OR, 1.75 ; CI, 1.03 to 2.98), dusts (OR, 3.00 ; CI, 1.19 to 7.52), or pesticides (OR, 3.82 ; 1.28 to 11.42).
Solvents and dusts also were associated with a higher risk of tubal-factor infertility (solvents : OR, 1. 95 ; CI, 1.08 to 3.52 ; dusts : OR, 2.87 ; CI, 1.05 to 7.88) and endometriosis (solvents : OR, 2.13 ; CI, 0.96 to 4.72 ; dusts : OR, 3.63 ; CI, 0. 99 to 13.28).
Video display terminal exposure was more likely to be found among those women diagnosed with endometriosis (OR, 3.69 ; CI, 1.50 to 9.13) and cervical-factor infertility (OR, 2.65 ; CI, 0.99 to 7.12).
Results suggest that among women with a medically confirmed diagnosis, fertility may be adversely affected by a variety of occupational chemical exposures.
Mots-clés Pascal : Exposition professionnelle, Médecine travail, Composé chimique, Irradiation, Rayonnement, Toxicité, Femme, Homme, Stérilité, Fertilité, Epidémiologie, Iowa, Etats Unis, Amérique du Nord, Amérique, Illinois, Reproduction pathologie
Mots-clés Pascal anglais : Occupational exposure, Occupational medicine, Chemical compound, Irradiation, Radiation, Toxicity, Woman, Human, Sterility, Fertility, Epidemiology, Iowa, United States, North America, America, Illinois, Reproduction diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0205515
Code Inist : 002B03L01. Création : 21/05/1997.