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  1. Fulltext. Risk of cancer and exposure to gasoline vapors.

    Article - En anglais


    Until the introduction of self-service around 1970, service station workers in the Nordic countries were exposed to gasoline vapors.

    Based on measurements reported in the literature, the 8-hour time-weighted average benzene exposure was estimated to be in the range of 0.5-1 mg/m3.

    We studied the cancer incidence in a cohort of 19,000 service station workers from Denmark, Norway, Sweden, and Finland.

    They were identified from the 1970 censuses and followed through 20 years, where 1,300 incident cancers were observed.

    National incidence rates were used for comparison.

    The incidence was not increased for leukemia (observed=28, standardized incidence ratio (SIR)=0.9,95% confidence interval (Cl) 0.6-1.3) nor for acute myeloid leukemia (observed=13, SIR=1.3,95% Cl 0.7-2.1).

    The incidence was slightly elevated for kidney cancer (observed=57, SIR=1.3,95% Cl 1.0-1.7) and for pharyngeal, laryngeal, and lung cancer.

    A 3.5-fold risk of nasal cancer was found (observed=12, SIR=3.5,95% Cl 1.8-6.1).

    This cohort exposed to gasoline vapors with benzene levels estimated to be 0.5-1 mg/m3 showed no excess risk of leukemia or acute myeloid leukemia, a 30% elevated risk of kidney cancer, and a previously unnoticed risk of nasal cancer.

    Mots-clés Pascal : Tumeur maligne, Exposition professionnelle, Essence, Benzène, Travailleur, Station service, Epidémiologie, Facteur risque, Incidence, Toxicité, Homme, Médecine travail, Danemark, Europe, Suède, Finlande, Pays Bas

    Mots-clés Pascal anglais : Malignant tumor, Occupational exposure, Gasoline, Benzene, Worker, Service station, Epidemiology, Risk factor, Incidence, Toxicity, Human, Occupational medicine, Denmark, Europe, Sweden, Finland, Netherlands

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0205349

    Code Inist : 002B03L06. Création : 21/05/1997.

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