The prevalence of cardiovascular disease (CVD) increases with advancing age in women, particularly after menopause.
CVD risk is lower in physically active women relative to their sedentary peers, but the responsible mechanisms are not well understood.
The aims of this study were to test the hypotheses that 1) physically active postmenopausal women demonstrate more favorable blood pressure (BP) - related risk factors for CVD than do sedentary healthy women and 2) women on hormone replacement therapy (HRT) also have more favorable levels of these CVD risk factors.
BP-related CVD risk factors were measured in physically active women (n=18 ; age 55 ± 1 yr ; n=8 on HRT) and in healthy less-active controls (n=34 ; age 59 ± 1 yr ; n=17 on HRT).
Maximal oxygen consumption was higher in the active group, whereas waist-to-hip ratio and waist circumference were lower (all P<0.005).
The active women demonstrated marginally lower (5-8 mmHg ; P<0.10) levels of casual, 24-h, and daytime systolic BP (SBP).
They also tended to have lower (P 0.11) daytime SBP loads (percentage of BP recordings>140/90 mmHg) and lower daytime and nighttime BP variabilities (P=0.04) and a reduced (P<0.007) SBP response to submaximal exercise.
Women on HRT tended to have lower (3-4 mmHg ; P=0.07 levels of 24-h and nighttime diastolic BP (DBP) relative to the nonusers and smaller (P<0.04) daytime and 24-h DBP loads. (...)
Mots-clés Pascal : Composition corporelle, Tissu adipeux, Postménopause, Facteur risque, Cardiopathie coronaire, Prévalence, Chimiothérapie, Traitement substitutif, Oestrogène, Caucasoïde, Appareil circulatoire pathologie, Race, Hormone stéroïde sexuelle, Homme, Femelle
Mots-clés Pascal anglais : Body composition, Adipose tissue, Postmenopause, Risk factor, Coronary heart disease, Prevalence, Chemotherapy, Replacement therapy, Estrogen, Caucasoid, Cardiovascular disease, Race, Sex steroid hormone, Human, Female
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0205322
Code Inist : 002B02O. Création : 21/05/1997.