To examine the relation between osteoarthritis of the hand and knee in a group of skeletons dating to the 18th and early 19th centuries from two sites in London.
Methods-This was a case-control study of 115 cases and controls matched for age and sex.
Cases were skeletons with osteoarthritis of the hands ; cases and controls were assessed for the presence of osteoarthritis of any compartment of the knee.
Cases had a significant odds ratio (OR) for osteoarthritis of the knee compared with controls : OR 5.98,95% confidence interval (CI) 1.25 to 56.37.
Cases with osteoarthritis of the distal interphalangeal (DIP), proximal interphalangeal (PIP), and first carpometacar-pal (CMC1) joints had increased but non-significant odds ratios for osteoarthritis of the knee in the order DIP>PIP>CMCl.
Cases with multifocal osteoarthritis of the hands had a significantly increased odds ratio for osteoarthritis of the knee : OR 11.67,95% CI 1.13 to 379.57.
Conclusions-The study confirms the association between osteoarthritis of the hand and the knee seen in contemporary populations and suggests that it is not of very recent origin.
Mots-clés Pascal : Arthrite, Articulation, Poignet, Main, Membre supérieur, Association, Genou, Membre inférieur, Etiopathogénie, Epidémiologie, Squelette, Homme, Angleterre, Grande Bretagne, Royaume Uni, Europe, Système ostéoarticulaire pathologie, Arthropathie
Mots-clés Pascal anglais : Arthritis, Joint, Wrist, Hand, Upper limb, Association, Knee, Lower limb, Etiopathogenesis, Epidemiology, Skeleton, Human, England, Great Britain, United Kingdom, Europe, Diseases of the osteoarticular system, Arthropathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0196998
Code Inist : 002B30A03C. Création : 21/05/1997.