To test the hypothesis that enthesophyte formation and osteophyte growth are positively associated and to look for associations between bone formation at different sites on the skeleton so that a simple measure of bone formation could be derived.
Methods-Visual examination of 337 adult skeletons.
All common sites of either enthesophyte or osteophyte formation were inspected by a single observer who graded bone formation at these sites on a 0-3 scale.
The total score for each feature was divided by the number of sites examined to derive an enthesophyte and an osteophyte score.
Cronbach's a and principal components analysis were used to identify groupings.
--Enthesophyte formation was associated with gender (M>F) and age.
There was a positive correlation between enthesophytes and osteophytes (r=0.65,95% confidence interval, 0.58 to 0.71) which remained after correction for age and gender.
Principal components analysis indicated four different groupings of enthesophyte formation.
By choosing one site from each group a simple index of total skeletal bone formation could be derived.
Conclusions-Osteophytes and enthesophytes are associated, such that a proportion of the population can be classified as « bone formers ».
Enthesophyte groupings provide some clues to aetiopathogenesis.
Bone formation should be investigated as a possible determinant of the heterogeneity of outcome and of treatment responses in common musculoskeletal disorders.
Mots-clés Pascal : Ostéophyte, Formation dépôt, Os, Insertion, Tendon, Relation, Etiopathogénie, Localisation, Etude statistique, Homme, Système ostéoarticulaire pathologie
Mots-clés Pascal anglais : Osteophyte, Deposit formation, Bone, Insertion, Tendon, Relation, Etiopathogenesis, Localization, Statistical study, Human, Diseases of the osteoarticular system
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0196993
Code Inist : 002B15H. Création : 21/05/1997.