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  1. Bone formers : osteophyte and enthesophyte formation are positively associated.

    Article - En anglais


    To test the hypothesis that enthesophyte formation and osteophyte growth are positively associated and to look for associations between bone formation at different sites on the skeleton so that a simple measure of bone formation could be derived.

    Methods-Visual examination of 337 adult skeletons.

    All common sites of either enthesophyte or osteophyte formation were inspected by a single observer who graded bone formation at these sites on a 0-3 scale.

    The total score for each feature was divided by the number of sites examined to derive an enthesophyte and an osteophyte score.

    Cronbach's a and principal components analysis were used to identify groupings.


    --Enthesophyte formation was associated with gender (M>F) and age.

    There was a positive correlation between enthesophytes and osteophytes (r=0.65,95% confidence interval, 0.58 to 0.71) which remained after correction for age and gender.

    Principal components analysis indicated four different groupings of enthesophyte formation.

    By choosing one site from each group a simple index of total skeletal bone formation could be derived.

    Conclusions-Osteophytes and enthesophytes are associated, such that a proportion of the population can be classified as « bone formers ».

    Enthesophyte groupings provide some clues to aetiopathogenesis.

    Bone formation should be investigated as a possible determinant of the heterogeneity of outcome and of treatment responses in common musculoskeletal disorders.

    Mots-clés Pascal : Ostéophyte, Formation dépôt, Os, Insertion, Tendon, Relation, Etiopathogénie, Localisation, Etude statistique, Homme, Système ostéoarticulaire pathologie

    Mots-clés Pascal anglais : Osteophyte, Deposit formation, Bone, Insertion, Tendon, Relation, Etiopathogenesis, Localization, Statistical study, Human, Diseases of the osteoarticular system

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0196993

    Code Inist : 002B15H. Création : 21/05/1997.