To identify which patterns of fetal growth, represented by different measurements of size at birth, are associated with increased blood pressure in children aged 8-11 years.
School based, cross sectional survey conducted in 10 towns in England and Wales in 1994.
3010 singleton children (response rate 75%) with physical measurements and information on birth weight from parental questionnaires.
Hospital birth records were examined for 1573.
Systolic and diastolic blood pressure at age 8-11 years.
In the whole group birth weight was inversely related to systolic pressure (regression coefficient - 1.48 mm Hg/kg ; 95%) confidence interval - 2.20 to - 0.76) after adjustment for current body size.
There was no significant association between birth weight and diastolic pressure.
The association with systolic pressure was much stronger in girls (-2.54 mm Hg/kg ; - 3.60 to - 1.48) than in boys (-0.64 mm Hg/kg ; - 1.58 to 0.30), with a significant difference between the sexes (P=0.006).
Among the other neonatal measures, head circumference and placental weight were inversely associated with subsequent blood pressure in girls, and placental ratio (placental weight : birth weight) was positively associated with blood pressure in boys.
Neither ponderal index at birth nor length : head circumference ratio was related to blood pressure in either sex. (...)
Mots-clés Pascal : Pression artérielle, Association, Poids naissance, Etude transversale, Milieu scolaire, Mesure pression différentielle, Systole, Diastole, Critère âge, Gestation, Placenta, Evaluation, Prévention, Homme, Appareil circulatoire pathologie
Mots-clés Pascal anglais : Arterial pressure, Association, Birth weight, Cross sectional study, School environment, Differential pressure measurement, Systole, Diastole, Age criterion, Pregnancy, Placenta, Evaluation, Prevention, Human, Cardiovascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0191752
Code Inist : 002B12B05B. Création : 21/05/1997.