The certification of poliomyelitis eradication in Europe will eventually require that countries demonstrate there is a minimal risk of wild poliovirus reintroduction and sustained transmission through unimmunized subpopulations such as ethnic minorities.
A serologic survey among a Gypsy community in Italy found that despite only 26% documented immunization coverage, serum neutralizing antibodies to poliovirus types 1,2, and 3 were detected in 81%, 94%, and 63% of the 86 persons studied.
While the high level of immunity found in this community may have been due to secondary spread of vaccine virus, the possibility of unrecognized circulation of wild polioviruses cannot be excluded.
Targeted immunization of such groups may be the most efficient means of eliminating the risk of importation-associated outbreaks.
Mots-clés Pascal : Poliomyélite antérieure, Virose, Infection, Poliovirus, Enterovirus, Picornaviridae, Virus, Effet biologique, Défaut, Immunoprophylaxie, Vaccination, Contamination, Immunisation adoptive, Etude statistique, Homme, Système nerveux pathologie, Système nerveux central pathologie, Moelle épinière pathologie, Gitan
Mots-clés Pascal anglais : Acute anterior poliomyelitis, Viral disease, Infection, Poliovirus, Enterovirus, Picornaviridae, Virus, Biological effect, Defect, Immunoprophylaxis, Vaccination, Contamination, Adoptive immunization, Statistical study, Human, Nervous system diseases, Central nervous system disease, Spinal cord disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0188121
Code Inist : 002B30A01C. Création : 21/05/1997.