The Pan American Regional Poliomyelitis Laboratory Network, developed to support the program to eradicate indigenous wild poliovirus transmission in the Americas, included 10 laboratories, distributed in eight countries in the Americas, organized according to the diagnostic procedures they regularly performed.
All laboratories isolated and typed virus in stool specimens, several did intratypic differentiation by nucleic acid probe hybridization, and 2 sequenced wild poliovirus isolates for molecular epidemiologic studies.
High performance of the network was maintained through comprehensive training of virologists, continuous monitoring of laboratory performance, and prompt investigation of problems.
Recommended field and laboratory procedures were regularly reviewed and revised to optimize sensitivity, specificity, and diagnostic efficiency.
Close integration of field and laboratory surveillance was achieved through frequent meetings between virologists and epidemiologists, effective communication of program priorities, and the distribution of weekly surveillance reports.
Mots-clés Pascal : Poliomyélite antérieure, Virose, Infection, Poliovirus, Enterovirus, Picornaviridae, Virus, Stratégie, Eradication, Surveillance, Etat sanitaire, Exploration virologique, Technique, Paralysie, Flasque, Résultat, Homme, Amérique, Système nerveux pathologie, Système nerveux central pathologie, Moelle épinière pathologie, Trouble moteur
Mots-clés Pascal anglais : Acute anterior poliomyelitis, Viral disease, Infection, Poliovirus, Enterovirus, Picornaviridae, Virus, Strategy, Eradication, Surveillance, Health status, Virological exploration, Technique, Paralysis, Flange, Result, Human, America, Nervous system diseases, Central nervous system disease, Spinal cord disease, Motor system disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0188114
Code Inist : 002B05C02A. Création : 21/05/1997.