Research with cognitively impaired subjects : Unfinished business in the regulation of human research.
1994 Annual Meeting of the American College of Neuropsychopharmacology. San Juan (PRI), 1994/12/13.
In 1978, the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research issued an important report that addressed the difficult ethical issues arising in research involving subjects with mental disabilities.
However, because of irreconcilable conflicts between the scientific community and rights-oriented advocacy groups, the federal government never issued the special regulations pertaining to these issues that had been envisioned by the National Commission.
Because these important ethical issues have not yet been adequately addressed by policy-making bodies, protection of cognitively impaired subjects depends too heavily on the diverse ethical sensitivities of individual investigators and on ad hoc responses of particular institutional review boards.
Researchers should support a credible and authoritative process for reexamining and resolving ethical issues relating to research with cognitively impaired subjects.
This can be accomplished without leading to the stalemate that doomed the National Commission's proposals.
The challenge is to forge a consensus on ethical guidelines and safeguards that will most reasonably accommodate the goals of protecting the dignity and well-being of research subjects while avoiding undue impediments to valuable scientific inquiry.
Mots-clés Pascal : Trouble psychiatrique, Trouble cognition, Démence sénile, Détérioration intellectuelle, Ethique, Recherche scientifique, Homme, Protection malade mental
Mots-clés Pascal anglais : Mental disorder, Cognitive disorder, Senile dementia, Intellectual deterioration, Ethics, Scientific research, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0186993
Code Inist : 002B18A. Création : 21/05/1997.