Natural rubber latex allergy is responsible for a wide spectrum of clinical symptoms, ranging from rhinoconjunctivitis to severe anaphylaxis, in both adults and children.
An association between allergy to latex and allergy to various fruits has been reported.
This study investigated the prevalence and clinical significance of latex sensitization in children seen in a university hospital allergy clinic.
A total of 453 consecutive children were screened in a 7-month period.
A detailed clinical history with particular attention to the past surgical history and the eventual presence of latex-or food-induced allergic symptoms was obtained.
Skin prick tests (SPT) for the more important inhalant allergens and foods were performed on all children.
In patients with positive latex SPT, latex challenge and additional SPT for some fresh foods (avocado, pineapple, apricot, grape, banana, pear, apple, orange, almond, and chestnut) were also performed.
RAST for the same food antigens, as well as patch test with latex and a standard battery of contact allergens, was also done.
Of 326 atopic children, 10 (3%) presented positive skin test to latex, but only five (1.5%) also had a positive clinical history to latex exposure.
Latex challenge was positive in 3/9 positive-latex-SPT children.
None of the nonatopic children had positive skin test to latex or symptoms to latex exposure. (...)
Mots-clés Pascal : Allergie, Latex, Caoutchouc naturel, Prévalence, Epidémiologie, Italie, Europe, Prick test, Test cutané, Exploration immunologique, Enfant, Homme, Immunopathologie
Mots-clés Pascal anglais : Allergy, Latex, Natural rubber, Prevalence, Epidemiology, Italy, Europe, Prick test, Skin test, Immunological investigation, Child, Human, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0184403
Code Inist : 002B06C05. Création : 21/05/1997.