An analysis of 8305 cases of carcinoid tumors.
Carcinoid tumors are unusual and most reports are anecdotal or limited in number.
A series of 2837 cases was published in 1975.
No recent large series is available.
The authors evaluated 5468 cases identified by the Surveillance, Epidemiology, and End Results (SEER) program of the National Cancer Institute (NCI) from 1973 to 1991 together with 2837 carcinoid cases previously registered by 2 earlier NCI programs.
To the authors'knowledge, the 8305 carcinoid tumors analyzed represent the largest current epidemiology series to date.
The most frequent sites for carcinoids were the gastrointestinal (GI) tract (73.7%) and the bronchopulmonary system (25.1%). Within the GI tract, most occurred in the small bowel (28.7%), appendix (18.9%), and rectum (12.6%). For all sites, age-adjusted incidence rates were highest in African American males (2.12 per 100,000 population per year).
Associated noncarcinoid tumors were frequent in conjunction with small intestinal (16.6%), appendiceal (14.6%), and colonic carcinoids (13.1%). The highest percentage of nonlocalized lesions were noted for pancreatic (76.1%), colonic (71.2%), and small intestinal carcinoids (70.7%) and this corresponded to their poor 5-year survival rates (34.1%, 41.6%, and 55.4%, respectively).
The best 5-year survival rates were recorded for appendiceal (85.9%), bronchopulmonary (76.6%), and rectal carcinoids (72.2%). These exhibited invasive growth or metastatic spread in only 35. (...)
Mots-clés Pascal : Tumeur carcinoïde, Intestin grêle, Côlon, Rectum, Bronchopulmonaire, Pancréas, Appendice vermiculaire, Incidence, Epidémiologie, Métastase, Pronostic, Etats Unis, Amérique du Nord, Amérique, Homme, Tumeur maligne, Intestin pathologie, Côlon pathologie, Rectum pathologie, Pancréas pathologie, Bronche pathologie, Poumon pathologie, Appareil respiratoire pathologie
Mots-clés Pascal anglais : Carcinoid tumor, Small intestine, Colon, Rectum, Bronchopulmonary, Pancreas, Vermiform appendix, Incidence, Epidemiology, Metastasis, Prognosis, United States, North America, America, Human, Malignant tumor, Intestinal disease, Colonic disease, Rectal disease, Pancreatic disease, Bronchus disease, Lung disease, Respiratory disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0178120
Code Inist : 002B13B01. Création : 21/05/1997.