There have been few reports about the frequency of multiple sclerosis (MS) in Spain.
We undertook a prevalence study in the province of Teruel, which is served by two hospitals as referral centres for a population of 143,680.
We found a total of 46 patients who fulfilled Poser's criteria for clinically definite or probable MS with a prevalence rate of 32/100,000 [95% confidence interval (CI) : 22.8-41.3]. The prevalence rates for males and females were 23.5 (95% CI : 12.3-34.7) and 40.6 (95% CI : 25.8-55.4) respectively.
We found an incidence rate of 2.2/year per 100,000 in the last 5 years.
The sex ratio (females/males) was 1.7. The mean age on prevalence day was 40.6 years (range : 15-76).
The clinical course was relapsing-remitting in 82% of patients, progressive in 9% and secondary progressive in the other 9%. The mean EDSS score was 3.73 (range : 1-8.5).
Our results confirm the hypothesis that Spain is an area at high risk for MS.
Mots-clés Pascal : Sclérose en plaque, Espagne, Europe, Sex ratio, Age, Disability Status Scale for Multiple Sclerosis Kurtzke, Prévalence, Homme, Système nerveux pathologie, Système nerveux central pathologie, Maladie inflammatoire, Epidémiologie, Teruel
Mots-clés Pascal anglais : Multiple sclerosis, Spain, Europe, Sex ratio, Age, Disability Status Scale for Multiple Sclerosis Kurtzke, Prevalence, Human, Nervous system diseases, Central nervous system disease, Inflammatory disease, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0177959
Code Inist : 002B17F. Création : 21/05/1997.