We examined 429 women, aged 20-80 years, randomly selected from the population register to establish normal values for bone mineral density (BMD) in Swedish women.
BMD of the spine and hip was measured by dual-energy X-ray absorptiometry (DEXA ; Hologic QDR 1000) and in the forearm by single photon absorptiometry (SPA ; Molsgaard ND-1100).
The recalled age of menarche was negatively correlated to BMD at all ages.
There was no significant change in BMD from 20-49 years at any site except a slight decline at Ward's triangle.
Bone loss was rapid at all sites during the first decade after menopause.
Thereafter, BMD declined slowly in the trochanter and total hip but more rapidly in the forearm, femoral neck, and Ward's triangle.
BMD in the spine even increased in the eighth decade probably due to osteoarthritis.
The average change in forearm BMD during the 15 perimenopausal years comprising mean age for menopause ± 2 SD (4<57 years) was - 0.4% per year in premenopausal females and - 1.6% per year in postmenopausal females.
The corresponding annual percental change was, for the spine, 0.2 and - 1.7 ; neck, - 0.7 and - 1.7 ; trochanter, 0.5 and - 1.5 ; and Ward's triangle, - 0.1% and - 2.2%, respectively.
Our normal values for lumbar spine BMD prior to menopause did not differ from published values or the manufacturer's normal values ; however, our spine BMD values for the first decade after menopause were significantly lower (=10%) than in other studies. (...)
Mots-clés Pascal : Densité, Os, Exploration, Spectrométrie absorption RX, Hanche, Rachis, Spectrométrie absorption, Photon, Avant bras, Epidémiologie, Etalon, Analyse corrélation, Ostéopénie, Homme, Femelle, Suédois, Exploration radiologique, Système ostéoarticulaire pathologie, Ostéopathie
Mots-clés Pascal anglais : Density, Bone, Exploration, X ray absorption spectrometry, Hip, Spine, Absorption spectrometry, Photon, Forearm, Epidemiology, Standard, Correlation analysis, Osteopenia, Human, Female, Swedish, Radiologic investigation, Diseases of the osteoarticular system, Bone disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0176837
Code Inist : 002B15A. Création : 21/05/1997.