Plasma retinol and indices of iron status were measured in 148 school children (6-12 years) receiving a soup fortified with iron and vitamin C for a period of 15 weeks.
The most significant change in serum iron (P=0.0005) and transferrin saturation (P=0.0002) was seen in subjects with plasma retinol = 40 mug/dl, while subjects with plasma retinol<20mug/dl showed no response.
Serum ferritin improved most in the retinol categories<40 mug/dl, suggesting that the absorption of iron was not impaired by marginal vitamin A status, but that it was rather the mobilisation of iron from stores that was affected.
Changes in vitamin A status correlated positively and significantly with changes in serum iron (r=0.37 ; P=0.0001) transferrin saturation (r=0.27 ; P=0.004) and haemoglobin (r=0.21 ; P=0.03), but negatively with serum ferritin (r=-0.28 ; P=0.003).
The presence of marginal vitamin A deficiency in a community may limit the effectiveness of an iron intervention programme and vitamin A status should therefore also be considered when such programmes are planned.
Mots-clés Pascal : Régime alimentaire enrichi, Fer, Acide ascorbique, Potage, Programme sanitaire, Etat nutritionnel, Rétinol, Alimentation, Nutrition, Micronutriment, Elément minéral, Vitamine, Enfant, Homme, Age scolaire, République Sud Africaine, Afrique, Produit alimentaire enrichi
Mots-clés Pascal anglais : Supplemented diet, Iron, Ascorbic acid, Soup, Sanitary program, Nutritional status, Retinol, Feeding, Nutrition, Micronutrient, Inorganic element, Vitamin, Child, Human, School age, South Africa, Africa, Fortified product
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0167477
Code Inist : 002B29B. Création : 21/05/1997.