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  1. Epidemiology of liver cirrhosis morbidity and mortality in Iceland.

    Article - En anglais

    Background 

    The mortality from liver cirrhosis in Iceland is the lowest in the Western world.

    Objective 

    To study the epidemiology of liver cirrhosis mortality and morbidity in Iceland and to obtain a reliable separation between alcoholic cirrhosis (AC) and non-alcoholic cirrhosis (NAC) by using multiple data sources.

    Methods 

    The study included the whole population of Iceland.

    Mortality was studied through death certificate data for the period 1951-90 and morbidity (clinical incidence) through hospital, autopsy and biopsy records for the period 1971-90.

    Results 

    The average mortality for AC in age group 20 years and older was 8.6 and for NAC 19.2 per 10h/year and the average clinical incidence was 22.1 per 106/year for AC and 25.9 per 106/year for NAC.

    In the morbidity study 44% of cases were due to AC.

    In the mortality study 24% of cases were due to AC but the data suggested an underreporting of AC for males at a rate of 30%. There was a significant decrease in AC mortality with time but no change in NAC.

    Average alcohol consumption of inhabitants aged over 15 years increased from 2.1 to 4.9 litres per year (130%) during the period 1951-90.

    Conclusion 

    The incidence of cirrhosis in Iceland is very low for both AC and NAC, accounting for only 0.2% of total deaths.

    The reasons are unknown.

    The low incidence of AC in Iceland is probably partly due to low alcohol consumption. (...)

    Mots-clés Pascal : Cirrhose, Foie, Incidence, Etiologie, Morbidité, Evolution, Mortalité, Epidémiologie, Homme, Islande, Iles Atlantiques, Appareil digestif pathologie, Foie pathologie

    Mots-clés Pascal anglais : Cirrhosis, Liver, Incidence, Etiology, Morbidity, Evolution, Mortality, Epidemiology, Human, Iceland, Atlantic Ocean Islands, Digestive diseases, Hepatic disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0166440

    Code Inist : 002B13C03. Création : 21/05/1997.