We measured 12 analytes in urine of 1000 adults living in the United States to establish reference range concentrations for pesticide residues.
We frequently found six of these analytes :
2,5-dichlorophenol (in 98% of adults) ;
2,4-dichlorophenol (in 64%) ;
1-naphthol (in 86%) ;
2-naphthol (in 81%) ;
3,5,6-trichloro-2-pyridinol (in 82%) ;
and pentachlorophenol (in 64%). The 95th percentile concentration (95thPC) for 2,5-dichlorophenol (indicative of p-dichlorobenzene exposure) was 790 mu/liter ;
concentrations ranged up to 8700 mug/liter. 2,4-Dichlorophenol concentrations ranged up to 450 mug/liter, and the 95thPC was 64 mug/liter. 1-Naphthol and 2-naphthol (indicative of naphthalene exposure) had 95thPCs of 43 and 30 mug/liter, respectively ;
concentrations of 1-naphthol ranged up to 2500 mug/liter.
Chlorpyrifos exposure was indicated by 3,5,6-tricholoro-2-pyridinol concentrations of 13 (95thPC) and 77 mug/liter (maximum observed).
Pentachlorophenol had a 95thPC of 8.2 mug/liter.
Other analytes measured included 4-nitrophenol (in 41%) ; 2,4,5. trichlorophenol (in 20%) ; 2,4,6-trichlorophenol (in 9.5%) ; 2,4-dichlorophenoxyacetic acid (in 12%) ; 2. isopropoxyphenol (in 6.8%) ; and 7-carbofuranphenol (in 1.5%). The 95thPCs of these analytes were<6 mug/liter. p-Dichlorobenzene exposure is ubiquitous ; naphthalene and chlorpyrifos are also major sources of pesticide exposure.
Exposure to chlorpyrifos appears to be increasing. (...)
Mots-clés Pascal : Pesticide, Exposition, Homme, Etats Unis, Amérique du Nord, Amérique, Surveillance biologique, Analyse quantitative, Urine, Liquide biologique, Epidémiologie, Polluant, Environnement, Phénol(2,5-dichloro)
Mots-clés Pascal anglais : Pesticides, Exposure, Human, United States, North America, America, Biological monitoring, Quantitative analysis, Urine, Biological fluid, Epidemiology, Pollutant, Environment
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0165034
Code Inist : 002B03G. Création : 21/05/1997.