In Israel, the reported prevalence of hepatitis-C virus (HCV) infection among blood donors is 0.44%. As we found a high prevalence of chronic hepatitis-B virus (HBV) and HCV infection in Jewish immigrants from Uzbekistan and Tajikistan (Bukharian Jews) among our general patient population, we determined the prevalence of HBV and HCV infection among « healthy » Bukharian Jewish immigrants by screening for HBV and HCV markers and risk factors in a population of Bukharian Jews in north Jerusalem.
A total of 27 (26.5%) of 102 patients were anti-HCV positive (by ELISA and confirmation tests).
The HCV positive patients were older and had a higher rate of liver enzyme abnormalities than were the HCV-negative patients (56.5 ± 2.3 versus 47.6 ± 1.8, p=0.003 ; and 14 of 27 versus 7 of 75, p<0.01, respectively).
HCV-positive patients with liver enzyme abnormalities were younger than HCV-positive patients without liver enzyme abnormalities (52.5 ± 3.0 versus 62.8 ± 2.8, p=0.02).
Sixteen patients (15.7%) were hepatitis-B surface antigen (HBsAg) carriers, and only two of these HBsAg carriers had liver enzyme abnormalities.
None of the HCV-positive patients were HBsAg carriers (0 of 27 among HCV-positive patients versus 16 of 75 among HCV-negative patients, p=0.0055).
Past infection with HBV was found in 67 examinees (66%) (45 of 75 HCV-negative patients and 22 of 27 HCV-positive patients, p=0.058). (...)
Mots-clés Pascal : Hépatite virale C, Virose, Infection, Hépatite virale B, Incidence, Juif, Emigration, Ouzbekistan, Asie, Tadjikistan, Facteur risque, Epidémiologie, Homme, Israël, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Viral hepatitis C, Viral disease, Infection, Viral hepatitis B, Incidence, Jew, Emigration, Uzbekistan, Asia, Tajikistan, Risk factor, Epidemiology, Human, Israel, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0156455
Code Inist : 002B05C02G. Création : 21/05/1997.