Antihypertensive medication noncompliance is common and leads to substantial morbidity for patients and increased health care costs for managed-care organizations.
A retrospective cohort study using pharmacy prescription profiles to estimate non-compliance was conducted to determine important risk factors for patient noncompliance with antihypertensive therapy for Medicaid enrollees participating in a managed-care plan.
The pharmacy and claims data for 1395 patients with uncomplicated hypertension who were enrollees of Tennessee Medicaid managed-care program were analyzed to determine the frequency of the enrollees'failure to obtain timely antihypertensive medication refills (hereafter referred to as refill failure) and to identify the predictors of refill failure.
Overall, refill failure occurred in 33% of 7413 refill opportunities studied, whereas refill failure occurred in 32% of the cases in which medication was dosed once daily and in 35% of the cases in which medication was dosed more than once daily.
For patients taking alpha-blockers, there was a significantly lower rate of refill failure (11.0%) than for patients taking angiotensin-converting enzyme inhibitors, direct vasodilators, and thiazide diuretics.
Patients taking calcium channel blockers, had a significantly lower rate of refill failure (38.5%) than for patients taking thiazide diuretics (45.5%). (...)
Mots-clés Pascal : Antihypertenseur, Chimiothérapie, Traitement, Hypertension artérielle, Homme, Observance médicamenteuse, Approvisionnement, Facteur risque, Etats Unis, Amérique du Nord, Amérique, Appareil circulatoire pathologie, Medicaid
Mots-clés Pascal anglais : Antihypertensive agent, Chemotherapy, Treatment, Hypertension, Human, Drug compliance, Supply, Risk factor, United States, North America, America, Cardiovascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0155935
Code Inist : 002B02F05. Création : 21/05/1997.